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Brilliant minds finding solutions to complex problems, made easy to understand. Making complex easy.

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EPR laboratory mechanical and electrical system

BioEmPiRe Centre, The University of Manchester

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We designed the mechanical and electrical building services for a new state-of-the-art BioEmPiRe Centre for Structural Biological Electron Paramagnetic Resonance (EPR) Spectroscopy, located in the Micheal Smith Building at The University of Manchester.

The centre launched in 2025 and is equipped with a new high-power (300 watt) EPR spectrometer and an integrated cryogen-free cooling system to enable the assessment of complex membrane proteins.

Our engineers delivered technical assistance and guidance at every stage of the project, from initial feasibility to final commissioning, ensuring seamless installation and optimal performance of the specialist laboratory equipment. 

The project won ‘Small Project of the Year Award’ at The University of Manchester’s Estates & Facilities Outstanding Achievement Awards 2025.

Project name

BioEmPiRe Centre for Structural Biological EPR Spectroscopy 

Client

University of Manchester

Location

Manchester, UK

Services provided

  • Mechanical and electrical design
EPR Magnet Photo 1

Solution

Our team has partnered with The University of Manchester for many years, regularly developing concept designs and feasibility reports for building services across the University’s property portfolio. During the concept stage, we discuss different options, outlining the pros and cons of each solution, together with budget costs. This approach helps reduce time spent exploring design in detail that may not be aligned with the project budget, ultimately saving our client time and money.

We worked closely with the university from project initiation to produce feasibility reports, which discounted three buildings before settling on the Michael Smith Building. We assessed if the building could house the heavy equipment, had suitable environmental conditions for the laboratory and had sufficient space to install and route the supporting services with minimal cost and disruption to the university.

Our mechanical and electrical engineers were critical to delivering the infrastructure to enable the specialist laboratory to operate at optimal conditions. To effectively study the proteins, cryogenic temperatures were required. The university chose to use liquid helium via a new helium compressor which can produce temperatures as low as 0.2 Kelvin. The helium compressor produces a significant amount of heat. The magnetic EPR spectrometer also generated a lot of heat energy that needed to be controlled. We provided the full detailed design for the liquid cooling solution to remove the heat from the laboratory equipment.

Collaborating with the University’s supply chain, we reviewed different options for water temperatures and pressures, plate heat exchangers, pumps, and pipe sizes to provide the most effective solution that balanced capital cost, operating cost, and space constraints.